VOLUME 18 NUMBER 1 (January to June 2025)

Physicochemical, antioxidant, and anti-tyrosinase property of standardized phenolics powder from mango seed kernel

Mango (Mangifera indica L.) is one of the major crops produced in the Philippines. In recent years, the mango industry is facing challenges with issues like infestations, seasonality, and competition, causing a decline in the global market share. To help alleviate the industry, mango by-products, such as seeds and peels, are being actively studied for their polyphenol content, which has potential benefits in pharmaceutical and cosmeceutical applications. In this study, we evaluated the physicochemical and bioactive properties of spray-dried phenolics from mango seed kernel (SPMK) across varying extraction volumes (1800 mL, 9000 mL, 14400 mL) using an optimized extraction and spray-drying process. Findings revealed that larger extraction volumes resulted in lower moisture content and higher water solubility index (WSI), indicating improved powder stability and solubility, with constant bulk density and tapped density. The total phenolic content (TPC) was maintained at 138.04 to 141.97 mg GAE/g across extraction volumes, with strong antioxidant activity and significant tyrosinase inhibition (IC₅₀: 6.62 to 6.91 µg GAE), demonstrating the potential of SPMK for high-value applications.